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OBJECTIVE: Ameloblastic fibroma (AF) is an uncommon benign
mixed odontogenic tumour with a relative frequency of between
1.5% and 4.5%. The epithelial component of AF resembles
ameloblastoma, while the stromal component appears as an
immature cell-rich myxoid tissue with an embryonic appearance.
The aim of this study was to analyze AF cases seen in two Tertiary
Dental Centres in Nigeria.
METHODS: The Oral Pathology records of University College
Hospital (UCH), Ibadan and the Obafemi Awolowo Teaching
Hospital (OAUTH), Ile Ife were searched for lesions diagnosed as
AF between the period of 1999-2015 for UCH and 2003 to 2013 for
OAUTH. Demograhic data including age, gender and site were
RESULTS: Fifteen cases of AF representing 3.1% of all odontogenic
tumours were reported. There were 8 (53.3%) males and 7 (46.7 %)
females giving a 1.2:1 male: female ratio. The age range was 12-63
years, with a mean age of 28.3 (±16.8) years. The peak age incidence
was in the second and third decades of life, both accounting for 10
(66.7%) cases. There was a mandibular predilection, with 14 (93.3%)
cases occurring in the mandible while only 1 (6.7%) case was found
in the maxilla.
CONCLUSION: This study showed that AF is a relative rare lesion
and the demographics were essentially similar to previous reports.
However, the mean age in this study was higher than those reported
by most studies. A larger multicentre study will be appropriate to
further investigate the differences obtained in this study and previous