African Journal of Oral and Maxillofacial Pathology and Medicine <p style="text-align: justify;">This current issue of the African Journal of Oral and Maxillofacial Pathology and Medicine (AJOMPM) consist mostly of the research work presented at the 2<sup>nd</sup> Conference of the IAOP- African held in Ghana in August 2017. The manuscripts published are in line with the journal’s aims to provide our readers with current research findings that will impact positively on the practice of Oral and Maxillofacial Pathology/Medicine, Forensic Odontology, Oral Biology and Oral/Maxillofacial Radiology worldwide.</p> <p style="text-align: justify;">The journal manuscripts include recent researches on the diagnosis of orofacial cancer in younger age group, pigmented oral lesion in sero-positive HIV patients, a review of ameloblastoma in a Nigerian population, and records of lip imprint for diagnosis and forensic analysis. In addition, some interesting case reports of salivary gland tumours were presented in the journal for our readers.</p> <p style="text-align: justify;">&nbsp;</p> <p style="text-align: justify;">&nbsp;</p> <p style="text-align: justify;">&nbsp;</p> <p style="text-align: justify;"><strong>Prof. Ojo M.A.</strong><br>Editor-in-Chief</p> African Journal of Oral and Maxillofacial Pathology and Medicine en-US African Journal of Oral and Maxillofacial Pathology and Medicine PREVALENCE OF JAW METASTASES OF MALIGNANT NEOPLASIA: A MULTICENTRE STUDY IN SOUTHERN NIGERIA <p><span class="fontstyle0">BACKGROUND: Orofacial metastases are rare and often omitted<br>in the differential diagnoses of jaw lesions until after the<br>histopathologic diagnosis. This is a study of the prevalence and the<br>clinicopathologic features of metastatic orofacial tumours.<br>METHODS: A retrospective 29-year study in three tertiary dental<br>centres in Southern Nigerian was carried out. All patients with<br>orofacial malignancies were identified from the medical records.<br>Those with histological diagnoses of metastatic tumours were<br>retrieved. The demographic data and clinicopathologic features of<br>each case were obtained. The proportions and descriptive variables<br>of the data were analyzed with SPSS, version 20.<br>RESULTS: Orofacial malignancy was diagnosed in 695 patients, of<br>which 6 were of metastatic origin giving a prevalence of 0.9 %. All<br>the metastases involved the jaw bones and were post-surgical. The<br>posterior mandible was the preferred site, (n=5, 83.3 %) and none<br>was observed in the oral soft tissues. The thyroid and the prostate<br>were the most frequent organ of origin in women and men<br>respectively. The mean age at presentation was 52.6 ± 13.9 (SD)<br>years. The male: female ratio was 1:2. Swelling (n=6, 100.0%) and<br>pain (n=3, 50.0%) were the commonest presentation. Mixed<br>radiopacity/lucency (n=4, 66.7%) was the commonest radiologic<br>appearance.<br>CONCLUSION: A low prevalence of orofacial metastases was<br>observed in this study. Destructive jaw swellings in elderly patients<br>after therapy for malignant neoplasms should be suspected and<br>evaluated to exclude metastases.</span> </p> M C Nwoga O O Soyele B F Adeyemi ##submission.copyrightStatement## 2019-11-11 2019-11-11 5 1 1 6 A CORRELATION OF CLINICAL PROFILE, COMPUTED TOMOGRAPHIC PATTERNS AND HISTOPATHOLOGIC TYPES OF ODONTOGENIC TUMOURS <p><span class="fontstyle0">OBJECTIVE: There is dearth of literature on computed<br>tomography (CT) patterns of odontogenic tumours in Nigerians.<br>This study aims to determine and correlate the clinical findings and<br>CT patterns with the histopathologic types of odontogenic tumours<br>in a Nigerian tertiary hospital.<br>METHODS: A retrospective review of the clinical records, CT<br>reports and available images, complemented with a review of the<br>histopathological slides and reports of patients, diagnosed of<br>odontogenic tumours over a 12-year period.<br>RESULTS: Twenty (20) patients were selected for this study based<br>on the above selection criteria. The patients’ mean age was 44 ±5.2<br>(S.E.) years and the peak age group was the 4</span><span class="fontstyle0">th </span><span class="fontstyle0">decade of life (n=7,<br>35.0%). There was equal male to female ratio (1:1), and the maxilla<br>(n=8, 40.0%) was the commonest solitary clinical sites.<br>Ameloblastoma (n=8, 40.0%) was the commonest clinical<br>diagnosis. The CT findings were mostly ill-defined lesional<br>margins (n=16, 80.0%) and solid CT density (n=12, 60.0%). Other<br>CT findings were heterogeneous contrast enhancement (n=5,<br>25.0%), soft tissue involvement (n=11, 55.0%), bone and soft tissue<br>infiltration (n=16, 80.0%). The most common histopathological<br>diagnosis were ameloblastic carcinoma (n=6, 30.0%) and plexiform<br>ameloblastoma (n=4, 20.0%). There was significant association of<br>heterogeneous contrast enhancement and solid CT pattern/density<br>with histological diagnosis of ameloblastic carcinoma (p=0.050)<br>and plexiform ameloblastoma (p=0.025) respectively.<br>CONCLUSION: This study observed similar CT patterns of bone<br>and soft tissue infiltration in malignant odontogenic tumours and<br>some variants of ameloblastoma. This study also suggests that<br>heterogeneous contrast enhancement and the solid CT patterns are<br>predictive of histological diagnosis of ameloblastic carcinoma and<br>plexiform ameloblastoma respectively.</span> </p> O F Omoregie E Ogbeide E V Orikpete ##submission.copyrightStatement## 2019-11-11 2019-11-11 5 1 7 13 CURRENT FINDINGS ON NUTRITION AND ORAL CANCER <p><span class="fontstyle0">Head and neck cancers are considered the sixth most common<br>cancers in males and the tenth most common in females. The<br>aetiology of oral cancer traditionally has been linked with different<br>forms of tobacco use and alcohol consumption. However, other<br>authors have reported oral cancer in people who do not use tobacco<br>or alcohol and suggested that other aetiological factors may be<br>associated with oral cancer development including diet and<br>nutrition, viruses, radiation, ethnicity, familial and genetic<br>predisposition, oral thrush, immunosuppression, use of mouthwash,<br>syphilis, dental factors and occupational risks. World Health<br>Organization (WHO) reports that 35 – 55% of human cancers and<br>about 15% of oropharyngeal cancers can be ascribed to dietary<br>deficiencies or imbalances. Foods and food groups such as fish,<br>vegetable oil, olive oil, bread, cereals, legumes, protein, fat, fresh<br>meat, chicken, liver, shrimp, lobster, and fibre have been associated<br>with protective effects on oral and pharyngeal cancers. This review<br>examines the relationship between different nutrients and<br>nutritional factors, and occurrence and prognosis of oral cancer.</span></p> A O Lawal ##submission.copyrightStatement## 2019-11-11 2019-11-11 5 1 21 30