SOLITARY PLASMACYTOMA: Report of a Rare Occurrence in the Mandible: Solitary Plasmacytoma

C. U. Okwuosa; M. C.  Nwoga; U. Otakhoigbogie; I. C.  Nwokike; C. U. Okechi; K. C. Nwankwo

Authors

Dr. C U Okwuosa Department of Oral Pathology and Oral Medicine, University of Nigeria Teaching Hospital Author
Dr. M C Nwoga Department of Oral Pathology and Oral Medicine, Faculty of Dentistry, University of Nigeria Author
U. Otakhoigbogie Department of Oral and Maxillofacial Surgery, Faculty of Dentistry, University of Nigeria Author
Dr. I C Nwokike Department of Oral and Maxillofacial Surgery, Faculty of Dentistry, University of Nigeria 4Department of Radiation oncology, University of Nigeria Teaching Hospital Author
Dr.C U Okechi Department of Oral and Maxillofacial Surgery, Faculty of Dentistry, University of Nigeria Author
Dr. K C Nwankwo Department of Radiation oncology, University of Nigeria Teaching Hospital Author

Keywords:

Extramedullary plasmacytoma, Multiple myeloma, solitary plasmacytoma

Abstract

BACKGROUND: Very little has been reported regarding
plasmacytomas in the oral and maxillofacial region and studies
cited were mostly in foreign literature apart from two cases from
Nigeria
Objective: The dearth of publications in African literature
informed the need to report a rare case of solitary plasmacytoma of
the mandible in a 52-year-old male patient

CASE REPORT: A 52-year-old male patient that presented at our
institution with an eight-month history of painless swelling of the left
mandible associated with difficulty in chewing. Histology diagnosed Non
Hodgkin lymphoma but immunohistochemical studies revealed tumour
cells with strong expression of CD138 and confirmed a diagnosis of
solitary plasmacytoma (SPB). The patient was treated with palliative
radiotherapy 30Gy in 10 fractions over two weeks.

CONCLUSION: SPB of jaw most commonly presents clinically as
a painless swelling, and radiographically as multilocular
radiolucency with ill-defined borders. Diagnosis of the SPB
depends on the microscopic evidence of plasma cell proliferation
and absence of any other bone involvement. Ancillary techniques
such as immunohistochemistry play an important role in
distinguishing SPB from other haematological diseases

SOLITARY PLASMACYTOMA: Report of a Rare Occurrence in the Mandible